This topic aims at supporting activities that contribute to one or several of the expected impacts for this call. To that end, proposals under this topic should aim for delivering results that are contributing to the following expected outcomes:
Failure to translate research findings into policy and practice prevents research from achieving maximum public health benefit. Despite substantial investment in clinical research in poverty-related diseases, including emerging and re-emerging infectious diseases and antimicrobial-resistant infections, exploitation and use of results beyond research groups to date remains limited. The barriers to an efficient uptake of research results include limited interaction between researchers, policymakers, patients’ community and other stakeholders, lack of experience in exploiting research results beyond academia, limited health systems capacity, affordability issues, and structural and cultural differences between the realms of research, programme planning and policymaking.
Proposals should address the following activities:
Applicants need to concisely describe any prior research findings and explain how the proposal builds on these results. Building on results from projects supported under previous EDCTP programmes is encouraged.
Proposals should present a sound assessment of the feasibility of the proposed work, especially as regards the planned clinical investigations. Realistic plans for recruiting trial subjects should be presented and corroborated by demonstrated success from previous studies. The proposals should justify the choice of populations to be enrolled into the trials and explain how they relate to the larger population. The full range of relevant determining characteristics (sex, gender, age, socio-economic status, etc.) needs also to be considered.
Proposals should describe how stakeholder views of the proposal’s relevance and the study design have been incorporated in the co-creation process of planning the research proposal. Proposals should indicate explicit plans for good participatory practices for engaging stakeholders at every step of the research life-cycle.
Proposals should provide details on the methodology for linking clinical research aspects with the translation into healthcare practice and policy.
Applicants are welcome to draw on any relevant lessons from knowledge translation in response to the COVID-19 pandemic.
It is essential that proposals bring together clinical researchers with experience in implementation research, health policy experts and end users.Cross-cutting Priorities:
The definition of health technology is the application of organized knowledge and skills in the form of medicines, medical devices, vaccines, procedures and systems developed to solve a health problem and improve quality of life.